Journal Publications

Project Data Sphere's success is ultimately measured by the practice-changing scientific insights discovered by the research community. We are proud to share the following list of peer-accepted publications, and we are grateful to the data providers, research scientists, and patients that make this possible.

Author(s) Datesort ascending Article Title Journal

Jue Hou, Rachel Zhao, Tianrun Cai

 June 2022 Temporal Trends in Clinical Evidence of 5-Year Survival Within Electronic Health Records Among Patients With Early-Stage Colon Cancer Managed With Laparoscopy-Assisted Colectomy vs Open Colectomy JAMA Network Open

Garrett S Bullock,Patrick Ward,Scott Peters, Amelia Joanna Hanford Arundale , Andrew Murray,Franco M Impellizzeri, Stefan Kluzek

 June 2022 Call for open science in sports medicine British Journal of Sports Medicine

Sophia Z. Shalhout, Kevin S. Emerick, Howard E. Kaufman, David M. Miller

 June 2022 A retrospective study of ipilimumab plus nivolumab in anti–PD-L1/PD-1-refractory merkel cell carcinoma Journal of Clinical Oncology

Chongyang Duan,Ao Yuan &Ming T. Tan

 May 2022 Robust estimates of regional treatment effects in multiregional randomized clinical trials with ordinal responses Journal of Biopharmaceutical Statistics

Jiang Y, Cai D, Shi S

 April 2022 Indirect Comparisons via Sorafenib for the Comparative Effectiveness of Two PD-1/PD-L1 Inhibitors to Treat Advanced Hepatocellular Carcinoma Patients without Prior Systemic Therapies Dovepress

Tomohiro Ohigashi, Kazushi Maruo, Takashi Sozu, Masahiko Gosho

 April 2022 Using horseshoe prior for incorporating multiple historical control data in randomized controlled trials Sage Journals

Hiroyuki Saeki, Takuji Komeda, Risa Tanaka, Yuki Yamatani & Hironori Sakai 

 March 2022 Estimation of a Suitable Number of Patients for Selective Safety Data Collection (ICH E19 Draft Guideline): When is the Safety Profile of a Drug Well Characterized? Therapeutic Innovation & Regulatory Science

T.Elumalai, C.Barker, T.Elliott, J.Malik, A.Tran, A.Hudson, Y.P.Song, K.Patel, J.Lyons, P.Hoskin, A.Choudhury, H.Mistry

 March 2022 Translation of Prognostic and Pharmacodynamic Biomarkers from Trial to Non-trial Patients with Metastatic Castration-resistant Prostate Cancer Treated with Docetaxel Clinical Oncology

Steffen Ventz, Sean Khozin, Bill Louv, Jacob Sands, Patrick Y. Wen, Leah Comment, Brian M. Alexander, Lorenzo Trippa

 March 2022 The Design and Evaluation of Hybrid Controlled Trials that Leverage External Data and Randomization Research Square

Siddharth Ramchandran, Gleb Tikhonov, Otto Lönnroth,  Pekka Tiikkainen, Harri Lähdesmäki

 March 2022 Learning Conditional Variational Autoencoders with Missing Covariates arXiv

Ahmad Y. Abuhelwa, Sarah Badaoui, Hoi-Yee Yuen, Ross A. McKinnon, Warit Ruanglertboon, Kiran Shankaran, Anniepreet Tuteja, Michael J. Sorich & Ashley M. Hopkins

 February 2022 A clinical scoring tool validated with machine learning for predicting severe hand–foot syndrome from sorafenib in hepatocellular carcinoma Cancer Chemotherapy and Pharmacology

Saki Nishiyama, Mamoru Narukawa

 February 2022 Impact of the Economic Status of the Patient's Country of Residence on the Outcome of Oncology Clinical Trials The Oncologist

Deborah Plana, Geoffrey Fell, Brian M. Alexander, Adam C. Palmer & Peter K. Sorger 

 February 2022 Cancer patient survival can be parametrized to improve trial precision and reveal time-dependent therapeutic effects Nature Communications

Liling Huang , Shiyu Jiang  & Yuankai Shi 

 February 2022 Prognostic significance of baseline neutrophil–lymphocyte ratio in patients with non-small-cell lung cancer: a pooled analysis of open phase III clinical trial data futuremedicine

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