Journal Publications

Project Data Sphere's success is ultimately measured by the practice-changing scientific insights discovered by the research community. We are proud to share the following list of peer-accepted publications, and we are grateful to the data providers, research scientists, and patients that make this possible.

Author(s) Datesort ascending Article Title Journal

Kaiwen Deng, Hongyang Li, and Yuanfang Guan

 February 2020 Treatment Stratification of Patients with Metastatic Castration-Resistant Prostate Cancer by Machine Learning iScience

Wei-xiang Qi, Lu Cao, Cheng Xu, Shengguang Zhao, Jiayi Chen

 February 2020 Adjuvant regional nodal irradiation did not improve outcomes in T1-2N1 breast cancer after breast-conserving surgery: A propensity score matching analysis of BIG02/98 and BCIRG005 trials The Breast

Mika Murtojarvia, Anni S. Halkolab, Antti Airolaa, Teemu D. Laajala, Tuomas Mirttid, Tero Aittokalliob, Tapio Pahikkalaa

 January 2020 Cost-effective survival prediction for patients with advanced prostate cancer using clinical trial and real-world hospital registry datasets International Journal of Medical Informatics

Timothe Menard, Bjorn Koneswarakantha, Donato Rolo, Yves Barmaz, Leszek Popko, Rich Bowling

 December 2019 Follow‑Up on the Use of Machine Learning in Clinical Quality Assurance: Can We Detect Adverse Event Under‑Reporting in Oncology Trials? Drug Safety

Justyna Mierzynska, Mekdes Taye, Madeline Pe, Corneel Coens, Francesca Martinelli, Katarzyna Pogoda, Galina Velikova, Vesna Bjelic-Radisic, Fatima Cardoso, Etienne Brain, Michail Ignatiadis, Martine Piccart, Geertjan Van Tienhoven, Robert Mansel, Hans Wildiers, Andrew Bottomley, on behalf of EORTC and EORTC Breast Cancer Group

 December 2019 Reference values for the EORTC QLQ-C30 in early and metastatic breast cancer European Journal of Cancer

Omar Abdel-Rahman

 December 2019 Effect of Body Mass Index on 5-FU-Based Chemotherapy Toxicity and Efficacy Among Patients With Metastatic Colorectal Cancer; A Pooled Analysis of 5 Randomized Trials Clinical Colorectal Cancer

Omar Abdel-Rahman

 November 2019 ECOG performance score 0 versus 1: impact on efficacy and safety of first-line 5-FU-based chemotherapy among patients with metastatic colorectal cancer included in five randomized trials International Journal of Colorectal Disease

Jiawei Zhou, Yutong Liu, Yubo Zhang, Quefeng Li and Yanguang Cao

 November 2019 Modeling tumor evolutionary dynamics to predict clinical outcomes for patients with metastatic colorectal cancer; a retrospective analysis American Association of Cancer Research

Omar Abdel-Rahman

 October 2019 Efficacy and toxicity outcomes of elderly castrate-resistant prostate cancer patients treated with docetaxel - A pooled analysis of 3 randomized studies Urologic Oncology: Seminars and Original Investigations

Wei-xiang Qi, Shengguang Zhao, and Jiayi Chen

 October 2019 Risk factors for developing osteonecrosis of jaw in advanced cancer patients underwent zoledronic acid treatment Future Oncology

Tobias Klatte, Kevin M. Gallagher, Luca Afferi, Alessandro Volpe, Nils Kroeger, Silvia Ribback, Alan McNeill, Antony C. P. Riddick, James N. Armitage, Tevita F. Aho, Tim Eisen, Kate Fife, Axel Bex, Allan J. Pantuck, Grant D. Stewart

 October 2019 The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma: development and evaluation using the ASSURE prospective clinical trial cohort BMC Medicine

Louis Dron, Shirin Golchi, Grace Hsu, Kristian, Thorlund

 September 2019 Minimizing Control Group Allocation in Randomized Trials Using Dynamic Borrowing of External Control Data – An Application to Second Line Therapy for Non-Small Cell Lung Cancer Contemporary Clinical Trials Communications

Omar Abdel-Rahman

 September 2019 Outcomes of metastatic breast cancer patients in relationship to disease‐free interval following primary treatment of localized disease; a pooled analysis of two clinical trials The Breast Journal

Toby Wilkinson, Siddharth Sinha, Niels Peek and Nophar Geifman

 August 2019 Clinical trial data reuse – overcoming complexities in trial design and data sharing Trials

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