Featured Journal Publications

Project Data Sphere’s success is ultimately measured by the practice-changing scientific insights discovered by the research community.  We are proud to highlight some of the peer-reviewed publications based on data from the PDS platform that have sparked changes in clinical or research practices.

Article Title Journal
Community mining of open clinical trial data Oncotarget
A DREAM Challenge to Build Prediction Models for Short-Term Discontinuation of Docetaxel in Metastatic Castration-Resistant Prostate Cancer JCO Clinical Cancer Informatics
Heterogeneous ensembles for predicting survival of metastatic, castrate-resistant prostate cancer patients F1000 Research
Sounding Board: Advantages of a Truly Open-Access Data-Sharing Model New England Journal of Medicine
Sounding Board: Advantages of a Truly Open-Access Data-Sharing Model New England Journal of Medicine
Overcoming barriers to develop a broad access data sharing platform Journal of Clinical Oncology
Prediction of Overall Survival for Patients with Metastatic Castration-Resistant Prostate Cancer: Development of a Prognostic Model Through a Crowdsourced Challenge with Open Clinical Trial Data The Lancet Oncology
Estimation of Tumour Regression and Growth Rates During Treatment in Patients with Advanced Prostate Cancer: A Retrospective Analysis The Lancet Oncology
Estimation of Tumour Regression and Growth Rates During Treatment in Patients with Advanced Prostate Cancer: A retrospective Analysis Lancet Oncology
Prediction of Overall Survival for Patients with Metastatic Castration-Resistant Prostate Cancer: Development of a Prognostic Model Through a Crowdsourced Challenge with Open Clinical Trial Data Lancet Oncology
"Threshold-crossing": A Useful Way to Establish the Counterfactual in Clinical Trials? Clinical Pharmacology & Therapeutics
The Prostate Cancer DREAM Challenge: A Community-Wide Effort to Use Open Clinical Trial Data for the Quantitative Prediction of Outcomes in Metastatic Prostate Cancer The Oncologist

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