Featured Journal Publications
Project Data Sphere’s success is ultimately measured by the practice-changing scientific insights discovered by the research community. We are proud to highlight some of the peer-reviewed publications based on data from the PDS platform that have sparked changes in clinical or research practices.
Author(s) | Date | Article Title |
Journal![]() |
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Anish B. Parikh, Alberto Martini, John Sfakianos, Matt D. Galsky, William K. Oh, Che-Kai Tsao |
February 2020 | Predicting toxicity-related docetaxel discontinuation and survival in metastatic castration-resistant prostate cancer (mCRPC) using open phase III trial data | Journal of Clinical Oncology |
Julia Wilkerson, Kald Abdallah, Charles Hugh-Jones, Greg Curt, Mace Rothenberg, Ronit Simantov, Martin Murphy, Joseph Morrell, Joel Beetsch, Daniel J. Sargent, Howard I. Scher, Peter Lebowitz,, Richard Simon, Wilfred D. Stein, Susan E. Bates, Tito Fojo |
January 2017 | Estimation of Tumour Regression and Growth Rates During Treatment in Patients with Advanced Prostate Cancer: A Retrospective Analysis | The Lancet Oncology |
Justin Guinney, Tao Wang, Teemu D. Laajala, Kimberly Kanigel Winner, J. Christopher Bare, Elias Chaibub Neto, Suleiman A. Khan, Gopal Peddinti, Antti Airola, Tapio Pahkkala, Tuomas Mirtti, Thomas Yu, Brian M. Bot, Liji Shen, Kald Abdallah, Thea Norman, Stephen Friend, Gustavo Stolovitzky, Howard Soule, Christopher J. Sweeney, Charles J. Ryan, Howard I. Scher, Oliver Sartor, Yang Xie, Tero Aittokallio, Fang Liz Zhou, James C. Costello |
January 2017 | Prediction of Overall Survival for Patients with Metastatic Castration-Resistant Prostate Cancer: Development of a Prognostic Model Through a Crowdsourced Challenge with Open Clinical Trial Data | The Lancet Oncology |
Monica M. Bertagnolli, Oliver Sartor, Bruce A. Chabner, Mace L. Rothenberg, Sean Khozin, Charles Hugh-Jones, David M. Reese, Martin J. Murphy |
March 2017 | Sounding Board: Advantages of a Truly Open-Access Data-Sharing Model | New England Journal of Medicine |
Tomas G. Neilan, Mace L. Rothenberg, Laleh Amiri-Kordestani, Ryan J. Sullivan, Richard M. Steingart, William Gregory, Subramanian Hariharan, Tarek A. Hammad, Joann Lindenfeld, Martin J. Murphy, Javid Moslehi, On Behalf of the Checkpoint Inhibitor Safety Working Group |
May 2018 | Myocarditis Associated with Immune Checkpoint Inhibitors: an Expert Consensus on Data Gaps and a Call to Action | The Oncologist |
Angela K. Green, Robert W. Corty, William A. Wood, Mathew Meeneghan, Katherine E. Reeder-Hayes, Ethan Basch, Matthew I Milowsky, Stacie B. Dusetzina |
May 2015 | Comparative Effectiveness of Mitoxantrone plus Prednisone versus Prednisone alone in Metastatic Castrate-resistant Prostate Cancer after Docetaxel Failure | The Oncologist |
Jiawei Zhou, Yutong Liu, Yubo Zhang, Quefeng Li and Yanguang Cao |
November 2019 | Modeling tumor evolutionary dynamics to predict clinical outcomes for patients with metastatic colorectal cancer; a retrospective analysis | American Association of Cancer Research |
Tobias Klatte, Kevin M. Gallagher, Luca Afferi, Alessandro Volpe, Nils Kroeger, Silvia Ribback, Alan McNeill, Antony C. P. Riddick, James N. Armitage, Tevita F. Aho, Tim Eisen, Kate Fife, Axel Bex, Allan J. Pantuck, Grant D. Stewart |
October 2019 | The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma: development and evaluation using the ASSURE prospective clinical trial cohort | BMC Medicine |
Junjie Hang, Lixia Wu, Lina Zhu, Khigiang Sun, Ge Wang, Jingjing Pan, Suhua Zheng, Kequn Xu, Jiadi Du, Hua Jiang |
June 2018 | Prediction of Overall Survival for Metastic Pancreatic Cancer: Development and Validation of a Prognostic Nomogram with Data from Open Clinical Trial and Real-World Study | Cancer Medicine |
Sebastian Pölsterl, Pankaj Gupta, Lichao Wang, Sailesh Conjeti, Amin Katouzian, Nassir Navab |
July 2017 | Heterogeneous ensembles for predicting survival of metastatic, castrate-resistant prostate cancer patients | F1000 Research |
Teemu D. Laajala, Justin Guinney, James C. Costello |
September 2017 | Community mining of open clinical trial data | Oncotarget |
Wei-xiang Qi, Lu Cao, Cheng Xu, Shengguang Zhao, Jiayi Chen |
February 2020 | Adjuvant regional nodal irradiation did not improve outcomes in T1-2N1 breast cancer after breast-conserving surgery: A propensity score matching analysis of BIG02/98 and BCIRG005 trials | The Breast |
Toby Wilkinson, Siddharth Sinha, Niels Peek and Nophar Geifman |
August 2019 | Clinical trial data reuse – overcoming complexities in trial design and data sharing | Trials |
Omar Abdel-Rahman |
June 2019 | Asian Americans have better outcomes of non-metastatic gastric cancer compared to other United States racial groups: A secondary analysis from a randomized study | World Journal of Gastrointestinal Oncology |