Featured Journal Publications

Project Data Sphere’s success is ultimately measured by the practice-changing scientific insights discovered by the research community.  We are proud to highlight some of the peer-reviewed publications based on data from the PDS platform that have sparked changes in clinical or research practices.

Article Title Journal
Comparative Effectiveness of Mitoxantrone plus Prednisone versus Prednisone alone in Metastatic Castrate-resistant Prostate Cancer after Docetaxel Failure The Oncologist
Estimation of Tumour Regression and Growth Rates During Treatment in Patients with Advanced Prostate Cancer: A Retrospective Analysis The Lancet Oncology
Prediction of Overall Survival for Patients with Metastatic Castration-Resistant Prostate Cancer: Development of a Prognostic Model Through a Crowdsourced Challenge with Open Clinical Trial Data The Lancet Oncology
Sounding Board: Advantages of a Truly Open-Access Data-Sharing Model New England Journal of Medicine
Heterogeneous ensembles for predicting survival of metastatic, castrate-resistant prostate cancer patients F1000 Research
Community mining of open clinical trial data Oncotarget
Myocarditis Associated with Immune Checkpoint Inhibitors: an Expert Consensus on Data Gaps and a Call to Action The Oncologist
Prediction of Overall Survival for Metastic Pancreatic Cancer: Development and Validation of a Prognostic Nomogram with Data from Open Clinical Trial and Real-World Study Cancer Medicine
Asian Americans have better outcomes of non-metastatic gastric cancer compared to other United States racial groups: A secondary analysis from a randomized study World Journal of Gastrointestinal Oncology
Clinical trial data reuse – overcoming complexities in trial design and data sharing Trials
The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma: development and evaluation using the ASSURE prospective clinical trial cohort BMC Medicine
Modeling tumor evolutionary dynamics to predict clinical outcomes for patients with metastatic colorectal cancer; a retrospective analysis American Association of Cancer Research
Adjuvant regional nodal irradiation did not improve outcomes in T1-2N1 breast cancer after breast-conserving surgery: A propensity score matching analysis of BIG02/98 and BCIRG005 trials The Breast
Predicting toxicity-related docetaxel discontinuation and survival in metastatic castration-resistant prostate cancer (mCRPC) using open phase III trial data Journal of Clinical Oncology