Featured Journal Publications

Project Data Sphere’s success is ultimately measured by the practice-changing scientific insights discovered by the research community.  We are proud to highlight some of the peer-reviewed publications based on data from the PDS platform that have sparked changes in clinical or research practices.

Article Title Journal
Generalizable EHR-R-REDCap pipeline for a national multi-institutional rare tumor patient registry Jamia Open
Particle Swarm Optimized Gaussian Process Classifier for Treatment Discontinuation Prediction in Multicohort Metastatic Castration-Resistant Prostate Cancer Patients IEEE Journal of Biomedical and Health Informatics
Consensus disease definitions for neurologic immune-related adverse events of immune checkpoint inhibitors Journal for ImmunoTherapy of Cancer
Semi-automated Conversion of Clinical Trial Legacy Data into CDISC SDTM Standards Format Using Supervised Machine Learning Methods of Information in Medicine
Immune-related adverse events associated with immune checkpoint inhibitors: a call to action for collecting and sharing clinical trial and real-world data Journal for ImmunoTherapy of Cancer
KMDATA: a curated database of reconstructed individual patient-level data from 153 oncology clinical trials Database
Immune Checkpoint Inhibition in Marjolin Ulcer: A Case Series Journal of Immunotherapy
The Use of External Control Data for Predictions and Futility Interim Analyses in Clinical Trials Neuro-Oncology
Predicting toxicity-related docetaxel discontinuation and overall survival in metastatic castration-resistant prostate cancer: a pooled analysis of open phase 3 clinical trial data Prostate Cancer and Prostatic Diseases
Real-world assessment of response to anti-PD-1 therapy in advanced cutaneous squamous cell carcinoma Journal of the American Academy of Dermatology
Predicting toxicity-related docetaxel discontinuation and survival in metastatic castration-resistant prostate cancer (mCRPC) using open phase III trial data Journal of Clinical Oncology
Adjuvant regional nodal irradiation did not improve outcomes in T1-2N1 breast cancer after breast-conserving surgery: A propensity score matching analysis of BIG02/98 and BCIRG005 trials The Breast
Modeling tumor evolutionary dynamics to predict clinical outcomes for patients with metastatic colorectal cancer; a retrospective analysis American Association for Cancer Research
The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma: development and evaluation using the ASSURE prospective clinical trial cohort BMC Medicine

Pages